Title : Role of stress echocardiography with dipyridamol in the diagnosis of myocardial ischemia by evaluation of coronary flow reserve
Abstract:
Introduction: Myocardial ischemia is a major cause of cardiovascular morbidity and mortality, Early diagnosis is essential to optimize treatment and improve the prognosis, Stress echocardiography with dipyridamole, in particular the evaluation of coronary flow reserve, constitutes a non-invasive tool for the detection of ischemia at an early stage.
Objective: To evaluate the diagnostic value of stress echocardiography with dipyridamole and measurement of coronary flow reserve in the left anterior descending artery (LAD) in the early identification of myocardial ischemia. Methodology: A prospective study conducted in our department during 2025 included 100 patients referred for suspected coronary artery disease. All underwent dipyridamole echocardiography with analysis of left anterior descending (LAD) coronary flow reserve. The results were compared with coronary angiography data.
Results: among included patients with a left anterior descending coronary flow reserve of less than 2 showed a sensitivity of 85% and a specificity of 95 %for the detection of myocardial ischemia. Dipyridamole echocardiography allowed for the early identification of microvascular abnormalities not detected by conventional tests.
In conclusion: dipyridamole echocardiography with coronary flow reserve measurement of the LAD represents a reliable and reproducible non-invasive technique for the early diagnosis of myocardial ischemia. Its use could improve risk stratification and guide optimal management of coronary patients
